Anti-DISC1 Antibody 抗体

¥480.00¥880.00

SKU: BA2902-2 分类: , 标签:
BA2902-2-western-blotting-result-273919
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产品货号: BA2902-2
规格价格: 0.1ml/480元; 0.2ml/880元
检验物种: human
应用: WB
克隆: Polyclonal

产品描述

技术细节
试剂盒内容
指标信息
应用数据和图片
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产品概况

产品名称 Anti-DISC1 Antibody 抗体
产品描述 多克隆抗人的Anti-DISC1 Antibody 抗体可用于WB免疫印迹
文献引用格式 Anti-DISC1 Antibody 抗体 (Boster Biological Technology, Wuhan, China. Catalog #BA2902-2)
应用范围 WB免疫印迹
抗体来源
免疫原 多肽
抗体规格 0.1ml/480元;0.2ml/880元

产品详情

克隆 多克隆
产品形态 液体
内容 200μg/ml亲和纯化抗体,0.01M PBS,30%甘油。
*可以提供无载体抗体。
储存条件 连续使用时4°C存储,保质期六个月;长期存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

指标相关信息 (来源: Uniprot.org)

小贴士:你可以利用tissue specificity信息来帮助设计阳性和阴性对照。对此有疑问请联系我们技术服务部门。

基因名 DISC1
基因全名 Disrupted in schizophrenia 1 protein
蛋白功能 Ubiquitous. Highly expressed in the dentate gyrus of the hippocampus. Also expressed in the temporal and parahippocampal cortices and cells of the white matter. .
Tissue Specificity Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation. .
Sequence Similarities Disrupted in schizophrenia 1 protein;DISC1;KIAA0457;
Uniprot ID DISC1: Q9NRI5

指标背景简介

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

产品图片

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DISC1(BA2902-2)(MW:94KD)U87,SHG细胞裂解,免疫印迹分析。